In order to analyze the influence of locomotive traction force on wheel-rail relationship, a locomotive track coupling dynamics model based on 60 kg/m and 60N rail was established in SIMPACK multi-body dynamics software, and the horizontal track and ramp were set up. The relationship between locomotive traction force and wheel-rail creep, maximum normal contact stress and RCF damage coefficient were analyzed. The results showed that the longitudinal creep rate and longitudinal creep force increase rapidly and the lateral creep force decreases with the increase of traction force, especially when the locomotive is running on the 60N rail. The longitudinal creep force on the inner side of the rail is changed by the direction of the traction force, which results in the change of the direction of the inner crack of the rail. Compared with the 60 kg/m rail, the 60N rail has a stronger ability to resist wear, but it is easy to produce rolling contact fatigue.